Page 23 - Inaugural HKU Urology Congress program book (high resolution) 2026 0723

Focal Therapy Fusion Biopsy

PROCEDURES OF FUSION BX 2.0

Fusion Bx is driven by a simple 4-step guided workflow that minimizes both training and procedural
WHAT IS IRREVERSIBLE ELECTROPORATION (IRE)? time. The stepper buttons allow urologists to advance through most of the procedure without having

The NanoKnife System utilizes a mechanism of action called irreversible electroporation (IRE) that to take their hand off the probe.
selectively targets cell membranes to achieve cell death.
1. STUDY
1. Electric Field Application 2. Membrane Permeabilization 3. Cell Death Any patient can be selected to view images, past biopsies and reports with

a few simple clicks. MRI scans can be imported from USB, DVD, network or
PACS.

2. SWEEP
Images of the prostate can be acquired with a simple rotation of the
ultrasound probe. A 3D model is generated from 2D ultrasound
WHAT ARE THE BENEFITS OF NANOKNIFE SYSTEM? images. Both end-fire and side-fire workflows are supported.

RELIABLE ABLATION UNMATCHED VERSATILITY
Electrical pulses to destroy all living cells within the Can treat all segments of the prostate, enabling physicians to
treatment area with no skip lesions. build expertise in one technology to optimize patient outcomes. 3. REGISTER
Four identifiable landmarks are used to align images, then semi-
GENEROUS MARGINS EASY INTEGRATION automatic segmentation and elastic registration are used to
Increased margin expansion without negatively Treatment typically takes one hour and seamlessly integrates account for differences in shape and size between the MRI and
impacting the rates of erectile function and into your practice utilizing existing imaging and biopsy skills. ultrasound.
incontinence in men.

LESS COLLATERAL DAMAGE CONSERVE FUTURE OPTIONS 4. BIOPSY
Ability to ablate across the urethra, nerves, and urinary Procedures can be repeated if necessary and do not interfere Suspicious lesions from the MRI are fused with the live ultrasound
sphincters to ensure treatment of lesions near vital with more standard treatments such as surgery or radiotherapy.
structures while preserving a patient’s quality of life. and shown as targets. Use the 3D model to navigate to targets for
quick and efficient biopsies.

PROCEDURES OF SONBLATE HIFU

STEP 1 WHAT ARE THE BENEFITS OF FOCAL FUSION?

The Sonablate probe is positioned in the patients’ rectum.
Accuracy

STEP 2 The Fusion Bx addresses 3 key sources of
inaccuracy: prostate deformation, patient
The treating physician will map out a customizes ablation plan. motion and registration.

STEP 3
Physician will initiates HIFU delivery creating indiviual lesions (similar in Efficiency
size to a grain of rice) that together ablate the desired volume. The 4-step guided workflow and semi-
robotic arm ease the procedure for both
WHAT ARE THE BENEFITS OF SONBLATE HIFU? physicians and patients.

The most customizable focal Comparable disease control to radical Accessibility
therapy treatment prostatectomy in the medium-term
The Fusion Bx supports all biopsy
Real-time ultrasound derived Multiple patient safety features approaches using the same equipment
feedback built-in to the device and workflow. Compatibility with third
Robust, long-term clinical No cutting, radiation, or hormones party therapeutic devices can facilitate
data focal therapy.